THURSDAY, OCTOBER 11, 2012
Registration & check-in 4pm, Opening reception 6pm
Keynote Talk
Fiona Watt, DPhil, Deputy Director of the Wellcome Trust Centre for Stem Cell Research, Herchel Smith Professor of Molecular Genetics and Deputy Director of Cancer Research UK Cambridge Research Institute: "Adhesion and epidermal differentiation"
FRIDAY, OCTOBER 12, 2012
Breakfast 7-8am, Talks 8am-4pm, Poster session 4-6pm
Session 1: Adhesion, Junctions and Cell Polarity in Tissue Morphogenesis
Carien Niessen, Session Chair
Carien Niessen, PhD, University of Cologne: "Cadherins and polarity proteins in morphogenesis"
Terry Lechler, PhD, Duke University: "Desmoplakin regulates MT polarity in epidermis"
Peter Koch, PhD, University of Colorado Denver: "Early roles of desmosomal cadherin receptors during development"
Valera Vasioukhin, PhD, Fred Hutchinson Cancer Research Center, University of Washington: "Hippo/warts/a-catenin pathway in morphogenesis and cancer"
Christina Van Itallie, PhD, National Heart, Lung, and Blood Institute, NIH: "Claudins and polarized cell functions"
Session 2: Dynamic Mechanisms for Regulating Adhesion Strength and Cell Behavior
Andrew Kowalczyk, Session Chair
Andrew Kowalczyk, PhD, Emory University: "Regulation of cell adhesion by cadherin endocytosis"
David Garrod, PhD, University of Manchester: "Regulating tissue hyperadhesion through desmosomes/PKC"
Sergey Troyanovsky, PhD, Feinberg School of Medicine, Northwestern University: "Novel mechanisms regulating cadherin-based adhesion"
Christopher Chen, MD, PhD, University of Pennsylvania, "Novel approaches for measuring adhesion and cell mechanics"
Eleni Tzima, PhD, University of North Carolina-Chapel Hill, "Mechanotransduction and signaling through adhesion receptors in vascular endothelium"
Poster Session
SATURDAY, OCTOBER 13, 2012
Breakfast 7-8am, Talks 8am-12pm, Optional hike or other excursion, 1-5pm, Dinner 6-8pm
Session 3: Cell Matrix and Migration in Wound Healing and Disease
John McGrath, Session Chair
John McGrath, MD, St. John's Institute/King's College London: "Inherited skin blistering: new insights from patients"
Jonathan Jones, PhD, Feinberg School of Medicine, Northwestern University: "Matrix, actin cytoskeleton and migration"
Reinhard Faessler, MD, PhD, Max Planck Institute of Biochemistry: "ILK/Kindlin orchestrate integrin signaling"
Sabine Werner, PhD, ETH Zurich-Hoenggerberg: "Wound healing"
Douglas DeSimone, PhD, University of Virginia: "Cadherin-dependent mechanosensitive cell signaling and the regulation of collective cell migration in Xenopus"
Banquet Dinner
Plenary Speaker: W. James Nelson, PhD, Stanford University, "The evolution of adhesion systems"
SUNDAY, OCTOBER 14, 2012
Breakfast 7-8am, Talks 8am-4:30pm, Dinner 6-8pm
Session 4: Coordinating Adhesion and Signaling in Epithelia
Kathleen Green, Session Chair
Kathleen Green, PhD, Feinberg School of Medicine, Northwestern University: "Coupling desmosomal cadherins to signaling in differentiation"
Andrea McClatchey, PhD, Harvard Medical School: "ERM proteins: coordinators of receptor signaling and intercellular contact in epidermal morphogenesis"
Spiro Getsios, PhD, Feinberg School of Medicine, Northwestern University: "Eph/Ephrin-adhesion intersection in the epidermis"
Eliane Mueller, PhD, University of Bern, "b-catenin and plakoglobin-dependent regulation of transcription"
Session 5: Diseases of Adhesion: From Bench to Bedside
Masayuki Amagai, Session Chair
Masayuki Amagai, MD, PhD, Keio University: "Mechanisms in pemphigus"
Jouni Uitto, MD, PhD, Thomas Jefferson University: "Disorders of the basement membrane"
John Stanley, MD, University of Pennsylvania: "Pathologic and non-pathologic autoantibodies in pemphigus"
Arnoud Sonnenberg, PhD, The Netherlands Cancer Institute: "Epidermal integrins in health and disease"
Jakub Tolar, MD, PhD, University of Minnesota: "Can bone marrow cells cure cutaneous diseases?"
MONDAY, OCTOBER 15, 2012
Breakfast, 7:30-8:30am; Airport bus departure, 9am
